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Sofosbuvir Selects the NS5B S282T Mutation In Vitro in Genotype 1-6 Replicons and Is Not
Cross-Resistant to Resistance-Associated Variants Selected by Other Classes of Antiviral Inhibitors
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Reported by Jules Levin
AASLD 2013 Nov 1-4 Wash DC
Simin Xu, Sonal Rajyaguru, Sophia Chiu, Christy Hebner, Evguenia S. Svarovskaia, Viktoria Gontcharova, Brian Doehle, Michael D. Miller, Hongmei Mo
Gilead Sciences, Inc., Foster City, CA
AASLD: No Resistance Detected in Four Phase 3 Clinical Studies in HCV Genotypes 1-6 of Sofosbuvir + Ribavirin With or Without Peginterferon - (11/07/13)
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