Conference Reports for NATAP

20th Conference on Retroviruses and Opportunistic Infections Atlanta, GA March 3 - 6, 2013 Back

Trends in and factors associated with virological failure among women conceiving on cART in Western Europe       Reported by Jules Levin CROI 2013   H Bailey, C L Townsend, M Cortina-Borja and C Thorne for the European Collaborative Study in EuroCoord UCL Institute of Child Health, University College London - 19% (74/396) of women had virological failure, with a median viral load of 1370 copies/ml (IQR 480, 6000). - The proportion with virological failure declined ten-fold from 34% (32/93) in 2000-01 to 3% (1/33) in 2010-11 (trend p<0.01, Figure 1); 64 of the 74 women with virological failure enrolled prior to 2006. - Median age 33 yrs; 56% from sub-saharan Africa, 33% had CD4 <350 - 37% of women were on a non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimen (mostly nevirapine);