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HIV discoverer: 'To develop a cure is almost impossible'
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Meera Senthilingam, for CNN
July 24, 2015
http://www.cnn.com/2015/07/23/health/francoise-barre-sinoussi-hiv/
Vancouver (CNN) She's the woman who co-discovered HIV in 1983, and won a Nobel Prize for her work. But next month, French scientist Francoise Barre-Sinoussi will retire from her lab.
She spoke with CNN at this week's International AIDS Society Conference, in Vancouver, about activism, the future of HIV and why there's still no cure
A cure for me is almost an impossible mission because the reservoir of cells is not only in the blood. How to eliminate all the cells which are reservoirs is why I say it's an impossible mission. They are everywhere -- in the gut, in the brain, in all the lymphoid tissue.
Even if you have a very efficient strategy, how you can make sure that there's not one or two cells still there and if one is there the virus will reappear again? That's why I say it's an impossible mission.
But you never know.
What about a "functional cure"?
I prefer to say remission (when the virus is brought down to low levels in the body) ... That's possible. I'm convinced one day -- I don't know when -- we will have a strategy to induce durable remission. I don't believe that we will have only one treatment. It will be a combination of treatments.
(But) we need both -- a cure and a vaccine.
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authored by Francoise Barre-Sinoussi and Jintanat Ananworanich
Is it time to abandon single intervention cure trials? - (09/25/15)
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HIV+ Fat Tissue is a HIV Reservoir & Inflammation Occurs Within the Fat Tissue due to HIV - 2 studies report - (09/28/15) .......[other] Major tissue reservoirs include lymphoid tissue (lymph nodes, spleen, thymus and bone marrow), gut-associated lymphoid tissue (GALT) and the central nervous system.
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