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Asymptomatic neurocognitive impairment (ANI) is associated with progression
to symptomatic HIV-associated neurocognitive disorders (HAND) in people with
HIV: results from The Ontario HIV Treatment Network (OHTN) cohort study.....
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......"Participants with ANI status at first visit were more likely than those who were NP-N to show progression to symptomatic HAND (Figure 1)."
from Jules: take a look at Table 2 - viral load <50, nadir CD4 <200 & current CD4 >500 do not hold up under multivariate analysis but in univariate analysis they perform better as possible predictors
Reported by Jules Levin
IAS Vancouver 2015 July 19-23
Presented by Sean B Rourke
S.B. Rourke1,2,3, J. Gill4,5, A. Rachlis3,6, C. Kovacs7, G. Arbess2, J. Brunetta7, A. Carvalhal2,3, C. Power5, R. Rosenes1, M. Atkinson1, L. Cysique8,9, T. Marcotte10,11, A. Burchell1,3, T. Bekele1
1The Ontario HIV Treatment Network, Toronto, Canada, 2St. Michael's Hospital, Toronto, Canada, 3University of Toronto, Toronto, Canada, 4Alberta Health Services, Calgary, Canada, 5University of Alberta, Calgary, Canada, 6Sunnybrook Hospital, Toronto, Canada, 7Maple Leaf Medical Clinic, Toronto, Canada, 8Neuroscience Research Australia, Sydney, Australia, 9University of New South Wales, Sydney, Australia, 10HIV Neurobehavioral Research Centre, San Diego, United States, 11University of California, San Diego, United States
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