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Future challenges for clinical care of an ageing population infected with HIV: a "geriatric-HIV" modelling study - [Healthcare Costs].... Very Sobering Analysis on Aging in HIV+....60% frail
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Very Sobering Analysis on Aging in HIV+....imagine the healthcare costs associatedwiththese outcomes, WHO will pay? Ryan White Care Act ? ACA? Consider it is cost effective to begin addressing aging problems now, it is time to hold a NATIONAL DISCUSSION on Aging & HIV....imagine global implications - burden, costs
Reported by Jules Levin
18th International Workshop on Comorbidities and Adverse Drug Reactions in HIV, September 12-13, 2016, New York
Guaraldi G1, De Francesco D2, Malagoli A1, Theou O3, Zona S1, Carli F1, Dolci G1, Mussini C1, Kirkland S4, Mussi C5, Cesari M6, Rockwood K7
20% are currently experiencing falls....20% currently disabled due to frailty - percent & numbers will increase every year [see graph below] ..... .....60% currently frail & 75% frail by 2030
by 2030 [in graph below on frailty] - 75% will have such significant frailty that a significant percent, perhaps 50%, will have to live in old age facilities the study author Giovanni Guaraldi said to me at the Workshop
....."In 2030, we predict that 29.9% of HIV-infected patients will have geriatric syndromes and 34% will be disabled." despite currently patients in this analysis have median 648 CD4 but CD8 doubled at 815; they had median nadir CD4 of 200 [86-300]
from Jules: .....50% report no exercising....8.9% report intense physical activity....22.5% report >10 cigarettes a day....in Table 3 its noteworthy (1) 36% had renal [kidney] insufficiency & 4.7% end-stage renal disease at age >65 [a big increase, 4-5 fold, in ESRD from earlier years] & 10% at age 50-54, & 20% by age 60-64 had renal insufficiency
(2) at age >65 - 22% had cardiovascular disease - 77% hypertension - 55% impaired glucose tolerance - 53% type 2 diabetes
(3) that by the age of 45-49 - 78% have lipodystrophy, 29% hypertension, 15% impaired glucose tolerance, 82% dyslipidemia, 11% cirrhosis, 68% vitamin Dinsufficiency, 12.7% fractures - 14% had type 2diabetesat age 50-54 increasing to 20% at age 55-59 which doubled to 53% at age >65
Reported by Jules Levin
18th International Workshop on Comorbidities and Adverse Drug Reactions in HIV, September 12-13, 2016, New York
Guaraldi G1, De Francesco D2, Malagoli A1, Theou O3, Zona S1, Carli F1, Dolci G1, Mussini C1, Kirkland S4, Mussi C5, Cesari M6, Rockwood K7
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