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Trends in Comorbid Conditions Mentioned with HIV Disease on Death Certificates, United States, 2000-2010 ...Comorbidities' Deaths Sharply Increasing/Leaders Ignore Problem
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from Jules: In figure 3 you will see sharp increases in deaths from 2007 to 2010 in HIV+ due to these comorbid conditions, these trends were likely to be worsened from 2010-to 2016: heart disease, kidney disease, cerebrovascular disease, chronic liver disease, and cancers - anal, lung, Oropharyngeal , colon & liver cancers - - there are several aging related posters at CROI starkly showing the disproportionate affect of aging among HIV+ vs HIV-negatives. HIV+ aging are sharply experiencing inability to function in daily living including limited mobility, increased cognitive function, increased fractures, increased kidney disease which will likely result in increased dialysis & end-stage renal disease etc. - Services & well designed research are needed but there is no leadership to address these concerns to address these concerns & implement programs for the services needed for these patients, from any corner including The White House, Congress, CDC & NIH/NIAID officials, patients/advocates or researchers/doctors. Self-centered aging HIV research funding by all parties ignores this group that was the original HIV-infected patient population back in the 1980s.
CDC Concludes:
"These results highlighting a growing need for chronic disease prevention and management in the aging U.S. HIV-infected population"
Reported by Jules Levin
CROI 2016 Feb 22-24 Boston
Kpandja (KP) Djawe, Kate Buchacz, Charles Rose, and John T. Brooks
Epidemiology Branch, Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
" HIV-infected patients are living longer due to advances in antiretroviral therapy (ART) but non-AIDS-related conditions (NARCs) in this aging population may limit survival.....Centers for Disease Control and Prevention......database was used to identify deaths associated with HIV (HIV deaths) in the United States among individuals, 30-49 years and 50-69 of age, that occurred between 2000 and 2010....to explore trends in AIDS-related conditions (ARCs) and NARCs recorded on death certificates along with HIV.
"among decedents aged 50-69 years, CoAs between HIV and both chronic heart disease and colon cancer increased while CoAs (coefficients of association) between HIV and both cryptococcosis and toxoplasmosis decreased during the 10-year period [Figure A-D]. Among decedents aged 30-49 years, the CoA between HIV and chronic heart disease increased but CoAs between HIV and other selected conditions did not change significantly [Figure A-D]. Conclusions: As the percentage of HIV deaths in the United States has declined, especially among young adults， both the percentage of deaths with a non-AIDS underlying cause and the associations between HIV and NARCs have increased. These trends highlight a growing need for chronic disease prevention in the aging U.S. HIV-infected population."
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