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CROI 2016 - Themed Discussion: Rants About HCV RAVS
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I have included links to 2 talks -
(1)Genotypic and Phenotypic Characterization of Clinical HCV NS5A Drug Resistance
Wei Huang, Monogram Biosciences, South San Francisco, CA, United States
(2)Retreatment with Harvoni of 34 Patients Treated Only for Short-Duration 4-6 Weeks with Harvoni in SYNERGY Trial, Eleanor Wilson, NIAID SYNERGY Trial
WEBCAST for Dr Huang's talk:http://www.croiwebcasts.org/console/player/29510?mediaType=audio&
She reported on an analysis of prevalence & drug susceptibility to NS5A resistance mutations (RAVs) on 973 samples submitted to Monogram for routine NS5A resistance testing.
![CROI1](../images/030516/030516-4/CROI1.gif)
Retreatment with Harvoni of 34 Patients Treated Only for Short-Duration 4-6 Weeks with Harvoni in SYNERGY Trial
Many of these patients had high level NS5A resistance but SVR Rates in the retreatment study were 85-90%
WEBCAST for Dr Wilson's talk:http://www.croiwebcasts.org/console/player/29514?mediaType=audio&
![CROI2](../images/030516/030516-4/CROI2.gif)
![CROI3](../images/030516/030516-4/CROI3.gif)
![CROI4](../images/030516/030516-4/CROI4.gif)
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