Aging At CROI 2019

Conference Reports for NATAP

Conference on Retroviruses
and Opportunistic Infections
Seattle, Washington
March 4-7, 2019


Aging At CROI 2019

	100+ reports NATAP CROI coverage Conference on Retroviruses and Opportunistic Infections Seattle, Washington March 4-7, 2019 COPD doubles heart attack risk with HIV regardless of smoking / "COPD and the risk of MI by type in people living with HIV" - (03/05/19) Sudden cardiac death risk higher with HIV--but not with sustained HIV control / "Sudden cardiac death among HIV-infected and -uninfected veterans" - (03/05/19) HIV tied to almost 2-fold lower breast cancer survival - (03/05/19) CROI: Successful HCV treatment does not affect rate of heart disease or non-AIDS cancer - (03/20/19) NASH IN HIV - CROI 2019 - (03/05/19) RETREATMENT OF HCV IN ADVANCED LIVER DISEASE / CROI 2019 - (03/05/19) Probiotic does not alter inflammation/activation markers in group on stable ART / "Assessing the probiotic effect in treated HIV: results of ACTG A5350" - (03/05/19) New fracture independently boosts death risk in big US HIV cohort - (03/14/19) BREAKING BONES IS BAD: INCIDENT FRACTURE AND MORTALITY IN THE HIV OUTPATIENT STUDY - 45% Increased Mortality Associated with Fracture Obesity & Weight Gain on Antiretroviral Therapy - (03/11/19) Obesity--but not frailty--predicts neurocognitive impairment with HIV - (03/08/19) CROI: Inflammation, Arterial Stiffness and Directly-Acting Antivirals in HCV and HIV/HCV, no beneft observed in this study - (03/20/19) Rebound Of HIV-1 In Cerebrospinal Fluid (CSF) After Treatment Interruption (TI) - (03/14/19) CROI: I Keep Forgetting HIV, Aging, and Cognitive Disorders - (03/29/19) Neurosymptomatic HIV-1 CSF Escape can Occur with Replication in CD4+ T Cells in the CNS - (03/13/19) Sex-specific Patterns in HIV-associated Cardiovascular Mortality in New York City - (03/18/19) HIV-Cognitive Impairment/Obesity-Overweight-Exercise-Efavirenz-Age "OBESITY IS INDEPENDENTLY ASSOCIATED WITH NEUROCOGNITIVE DECLINE IN HIV".....16% had neurocognitive impairment (NCI) & 6% frailty at baseline (03/08/19) CROI: THE PROJECTED AGE DISTRIBUTION OF WHITE, BLACK, AND HISPANIC MSM ON ART, 2009-2030 / 20% White MSM Projected to be over 70 by 2030 - (03/28/19) CROI: Changes in Kidney Function Among MSM Initiating On-Demand TDF/FTC for HIV Pre-Exposure Prophylaxis - (03/29/19) Clinical Outcomes in Persons Coinfected with HIV and HCV: Impact of HCV Treatment - (03/07/19) INCIDENT DIABETES AND GLUCOSE CONTROL AFTER HCV TREATMENT WITH DAAS IN ERCHIVES - (03/07/19) CROI: Earlier Age of Onset and Higher Prevalence of Comorbidities in People Living with HIV: A Population-Based Cohort Study in British Columbia, Canada - (03/28/19) CROI: PROJECTED GROWTH AND NEEDS OF AGING PLWH IN HRSA'S RYAN WHITE HIV/AIDS PROGRAM .....from 2010 through 2030 % > 50 years old doubles with curve sharply increasing-see graph below - (03/28/19) CROI: Suicide rates among adults living with HIV, 2000-2015 - (03/28/19) Yearly suicide rate in white men with HIV usually far exceeds rate in US population - (03/08/19) NHPC: CDC Reports 57% Viral Suppression Rates - (03/27/19) CROI: AIDS illness, living in US South, lower CD4s linked to longer hospital stay with HIV - (03/26/19) ART IN EARLY INFECTION IMPROVES NEUROCOGNITION REGARDLESS OF INFECTION DURATION - (03/19/19) but not in all cases RELAPSE OF SYMPTOMATIC CSF HIV ESCAPE UPON PREVIOUSLY OPTIMIZED C-ART REGIMEN CHANGES - (03/18/19) Successful HCV treatment does not affect rate of heart disease or non-AIDS cancer - (03/12/19) Higher cardiovascular risk in older HIV group tied to worse cognitive function - (03/08/19) Higher risk of recurrent venous thromboembolism with HIV in Dutch national study - (03/07/19)