icon-    folder.gif   Conference Reports for NATAP  
 
  Conference on Retroviruses
and Opportunistic Infections
Boston USA
March 8-11, 2020
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Comorbidities at CROI - mortality, aging.....
 
 
  Comorbidities at CROI- mortality, women experience more comorbidities, physical function decline/frailty high in older HIV+, diabetes, cardiovascular disease, excess cancer & coronary deaths, weight gain, fat, visceral fat, fat & metabolics, 6 brain studies, mitochondrial dysfunction/cognitive function, Low-Level Viremia risks, testosterone, insomnia/sleep, epigenetic aging before & after ART, liver disease: HCC rates, fibrosis-cirrhosis improvements, fat liver disease
 
Increased overall life expectancy but not comorbidity-free years for people with HIV - (03/27/20)
 
INDIVIDUAL AND POPULATION-LEVEL IMPACT OF HCV TREATMENT AMONG PEOPLE WHO INJECT DRUGS -(04/13/20)
Probability of cirrhosis declined from 2015 to 2018 from about 17% to about 7%, PWIDs Baltimore ALIVE Cohort due to DAAs. For every year since DAA treatment the odds of cirrhosis decreased by 56%. PLWH had higher rates of cirrhosis & those with higher HIV viral loads had higher rates of cirrhosis-these also had the higher log mean liver stiffness
 
IMPACT OF ANTIRETROVIRAL THERAPY INITIATION ON EPIGENETIC AGING AND TELOMERE LENGTH - (04/06/20)
Age advancement (EA minus chronological age) significantly improved after ART initiation (BL: 8.3 vs W96: 6.5 years, p=0.007). EA stabilized and EAA slowed in the majority of patients after starting ART. However, an age advancement of 6.5 years persisted after the first two years of successful ART.
 
MORTALITY AMONG PEOPLE WITH HIV WITH A HISTORY OF INJECTION DRUG USE, NEW YORK CITY, 2008-2017 - (04/07/20)
 
Much Higher Death Rate After Cancer Diagnosis in People With HIV - (03/20/20)
 
Mortality 4-Fold Higher With HIV in Canadian Group--in Sync With Comorbidity Tally - (03/11/20)
 
Less Coronary Intervention, Higher Mortality in HIV+ People With Acute Coronary Syndrome - (03/17/20)
 
GREATER WEIGHT GAIN AFTER SWITCH TO INSTI-BASED REGIMEN FROM NNRTI VS. PI REGIMENS
 
HIV Severity and Incident Heart Failure Among Adults in a Large Healthcare System - (03/11/20)
 
Low-level viremia during ART and the risk of death, AIDS, and serious non-AIDS events -(03/31/20)
 
Liver Cancer Rate Rising Since 1996 in North Americans With HIV - (03/18/20)
 
CAUSES OF DEATH IN PERSONS WITH AND WITHOUT HCV INFECTION - (03/18/20)
 
Doubled Risk of non-HIV Mortality in US People at Risk for HIV - (03/11/20)
 
Post-Discharge Outcomes Following Acute Coronary Syndrome in HIV [ Disparities for PLWH ] -(04/09/20)
 
Understanding Who Does and Does Not Gain Weight with Integrase Inhibitors (INSTI) - (04/01/20)
 
Women with HIV Have High Overall Burden and Early Accrual of Non-AIDS Comorbidities - (03/31/20)
 
EFFECTS OF HIV, AGE, AND SEX ON SKELETAL MUSCLE MASS AND DENSITY -(04/01/20)
 
Baseline and Acquired Comorbidities in Patients Initiating ART in the HOPS, 2008-2018 -(04/07/20)
Females were more likely than males to have obesity (Rate Ratio [RR] 2.02, 95% Confidence Interval [95%CI]: 1.71-2.39), diabetes (RR 2.00, 95%CI: 1.43-2.80), hepatitis-C (RR 1.74, 95%CI: 1.23-2.46), depression (RR 1.40, 95%CI 1.23-1.59), and psychosis (RR 2.09, 95%CI: 1.08-4.05) (Figure 2).
 
EFFECTS OF VIRAL LOAD ON NEUROIMAGING AND NEUROPSYCHOLOGICAL PERFORMANCE - (03/31/20)
 
BRAIN AGE BASED ON SLEEP ENCEPHALOGRAPHY IS ELEVATED IN HIV+ ADULTS ON ART -(04/08/20)
 
50% PREVALENCE OF PHYSICAL FUNCTION IMPAIRMENT AND FRAILTY IN MIDDLE-AGED PWH - age 46-55 -(03/27/20)
 
MITOCHONDRIAL DNA, COGNITIVE FUNCTION, AND FRAILTY IN OLDER ADULTS WITH HIV - (03/17/20)
 
EFFECTS OF HIV INFECTION AND IMMUNE REGULATION ON LONGITUDINAL LUNG FUNCTION DECLINE (03/27/20)
 
Adipocyte Dysfunction Despite Reduced Adipose Inflammation in Diabetics with HIV - (04/01/20)
 
Glucose Upsets Tied to Worse Physical Function in Men With or Without HIV - (03/11/20)
 
Rising BMI Tied to Risk of Diabetes But Not CVD in D:A:D Analysis - (03/17/20)
 
Initial Weight, Low CD4/CD8, Low Activity Drive Weight Gains After InSTI Switch - (03/11/20)
 
Predicted 10-year risks of diabetes and cardiovascular disease in the ADVANCE trial -(03/17/20)
 
EFFECT OF ANTICHOLINERGIC MEDICATIONS ON BRAIN INTEGRITY IN OLDER HIV-POSITIVE ADULTS -(03/23/20)
 
Starting ART With a PI or an InSTI (Mainly Raltegravir) May Heighten Risk of Diabetes - (03/17/20)
 
Themed Discussion FAT IN FOCUS - (03/11/20)
 
METABOLIC COMPLICATIONS OF HIV AND ITS THERAPIES (03/17/20)
 
Testosterone Use Tied to Signals of Atherosclerosis Progression in Men With HIV - (03/11/20)
 
HORMONE USE AND HIV ALTER CARDIOVASCULAR BIOMARKER PROFILES IN TRANSGENDER WOMEN - (03/11/20)
 
CLINICAL PREDICTORS OF LIVER FIBROSIS PRESENCE & PROGRESSION IN HIV-ASSOCIATED NAFLD - (03/12/20)
 
INVESTIGATION OF CLASSIC AND HIV-RELATED FACTORS FOR HEPATIC STEATOSIS AMONG PWID - 20% ALIVE Cohort (04/02/20)
 
RENAL IMPAIRMENT IN A PREEXPOSURE PROPHYLAXIS IMPLEMENTATION COHORT IN AUSTRALIA (04/10/20)
 
VISCERAL FAT IS A PREDICTOR OF LIVER FIBROSIS AND FIBROSIS PROGRESSION IN PEOPLE LIVING WITH HIV -(03/17/20)
 
NAFLD AND LIVER FIBROSIS PREDICT HIGH CARDIOVASCULAR RISK IN HIV-MONOINFECTED PATIENT - (04/02/20)
 
Diabetes, Weight Gain, & Integrase Inhibitor Use in North American HIV+ Persons - (04/04/20)
 
GREATER INCIDENCE OF DIABETES OVER 10 YEARS AMONG DEPRESSED US VETERANS WITH HIV - (04/04/20)
 
Predicted Rise in Diabetes Risk With TAF/FTC+DTG Versus TDF/FTC+DTG - - (03/12/20)
 
INSOMNIA AND RISK OF INCIDENT MYOCARDIAL INFARCTION AMONG PEOPLE LIVING WITH HIV - (03/13/20)
 
Use of D/C/F/TAF With Neurologic/Psychiatric Comorbidities: AMBER Subgroup Analysis - (03/16/20)
 
HIV DNA DETECTED IN IMMUNE CELL SUBSETS IN CSF DURING ART - (03/27/20)
 
Effects of HIV on Myelin Maps - (03/27/20)
 
PWH had a greater burden (5x) of primarily eccentric arterial wall enhancement compared with persons without HIV - (03/20/20)
 
PET IMAGING OF SYNAPTIC DENSITY IN HIV: PRELIMINARY FINDINGS FROM A PILOT STUDY - (03/27/20)
 
SINGLE-CELL GENOMIC ANALYSIS OF BLOOD AND CSF T CELLS IN HIV+ AND HIV- ADULTS......T Cell Exhaustion in CNS HIV - (03/17/20)
 
Retinal Thinning in Well-Controlled HIV-infected Patients - (03/23/20)
 
EFFECTS OF HIV INFECTION AND IMMUNE REGULATION ON LONGITUDINAL LUNG FUNCTION DECLINE - (03/30/20)
 
Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV Disease "LIFE HIV Study" (03/30/20)
 
Losartan does not improve lymphatic tissue fibrosis or T-cell recovery in HIV infection (04/01/20)
 
150+ NATAP CROI Reports - Conference on Retroviruses and Opportunistic Infections -
Boston USA
March 8-11, 2020
 
EASL: Summary from EASL 2018 for Hepatitis C (HCV) HCV in 2018: Success stories and remaining challenges? - Prof. Dr. J.K. Rockstroh Department of Medicine I University of Bonn Sigmund-Freud-Str. 25 53105 Bonn Germany