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Prevalence and Risk Factors of Chronic Kidney Disease in an HIV Infected Minority Urban Population
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Reported by Jules Levin
ICAAC/IDSA Oct 28 2008 Wash DC
Marcus Pereira, M.D. M.P.H., Benjamin Miko, M.D., Pedram Fatehi, M.D. M.P.H.,
Rebecca Hasley, Karen Brudney, M.D.,
Magdalena Sobieszczyk, M.D. M.P.H.
New York Presbyterian Hospital - Columbia University Medical Center
AUTHOR CONCLUSIONS
Although lower than African Americans, the prevalence of CKD among Latinos with HIV is high: in this study at this institution- 25% overall CKD, 29% in AAs, 23% for Latinos.
The progression of CKD among African-Americans and Latinos with HIV may be different.
Major risk factors for CKD included age >50 and hypertension
Among patients with HIV, Latinos may not have the same risk-factors for developing CKD as African-Americans.
Prospective cohort studies will be required to elucidate modifiable risk factors of CKD progression among minorities.
BACKGROUND
Chronic kidney disease (CKD) is an important complication of HIV in the era of highly active antiretroviral therapy (HAART), especially among minority populations.
African Americans (AA) are disproportionally affected and have been
typically studied.
We aimed to study the prevalence and risk factors of CKD among Latino HIV patients.
METHODS
--Case Control
--Inclusion criteria:
--HIV infected patients with at least 3 clinic visits between 1/1/2005 and 6/30/2007.
-- 2 consecutive labs, at least 3 months apart:
-- Urine albumin ≦ 1+
-- Spot urine protein to creatinine ratio ≦ 100 mg/dl
-- GFR ≦ 90
-- Control group:
Systematic random sampling of 10% of non-CKD patients
RESULTS
Baseline Characteristics
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