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High incidence rate of HCV reinfection after treatment of acute HCV infection in HIV-infected MSM in Amsterdam
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Reported by Jules Levin CROI 2011 March 2 Boston
Femke Lambers*1, Maria Prins1,2, Xiomara Thomas2, Richard Molenkamp2, Jan van der Meer2 and Janke Schinkel2;
1Public Health Service, Amsterdam, The Netherlands~ 2Academic Medical Center, Amsterdam, The Netherlands
"Of the 26 persons with follow-up after 2 months post-treatment, 7 were reinfected with HCV at a certain time point (all within 2 years)."
"Most patients switched from genotype 1 to 4 or from 4 to 1. One person had a clade switch and of another person genotype of reinfection is unknown."
Results
We included 28 persons of whom 2 relapsed within 2 months
after treatment. Of the 26 persons with follow-up after 2
months post-treatment, 7 were reinfected with HCV at a
certain time point (all within 2 years). Most patients switched
from genotype 1 to 4 or from 4 to 1. One person had a clade switch
and of another person genotype of reinfection is
unknown. See table 1 for characteristics and follow-up time.
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