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EASL Clinical Practice Guidelines: Management of chronic hepatitis B virus infection 2012
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Journal of Hepatology July 12 2012
The objective of this manuscript is to update the recommendations for the optimal management of chronic HBV infection
April 2012, EASL's revised CPGs on the Management of Chronic Hepatitis B (originally released in October 2008) now include; modified indications for liver biopsy and treatment for HBeAg-negative patients, new stopping rules for pegylated interferon-alfa therapy, amended recommendations for patients with partial virological response at 12 months of therapy with entecavir (ETV) or tenofovir (TDF), a replacement of the add-on strategy for resistance (better focus on lamivudine resistance) - replaced by a switch strategy, recommendations for less frequent HBV DNA testing under ETV or TDF, and more detailed recommendations for specific subgroups (particularly for HBV & pregnancy and for HBV & immunosuppression).
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