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A Meta-Analysis of the Differences in ART Virologic Failure Rates in Randomized Clinical Trials: Do Blacks Consistently Have Lower ART Efficacy and Poor Treatment Outcomes?
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Reported by Jules Levin
XIX International AIDS Conference
July 22-27, 2012
Washington DC, USA
"Black patients consistently have lower rates of virological success with an Odds Ratio of 0.52 [48% lower] (p < 0.0001) when compared with their racial counterparts......racial disparity should be of concern to investigators and the community. Further research is needed to assess the potential differences in pharmacokinetics, psychosocial barriers, models and tools to measure adherence, and analysis of care delivery models that facilitate greater virologic outcome"
D Spencer,1 C Evans,2 H Kwakwa,3 I Walker,4 L Temme,4 and MK Rawlings4
1Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA; 2AIDS Arms, Inc., Dallas, TX, USA;
3Philadelphia Department of Public Health, Philadelphia, PA, USA; 4Gilead Sciences, Inc., Foster City, CA, USA
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