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Jak inhibitors exhibit a novel mechanism of HIV inhibition
in primary human and rhesus macaque
macrophages and lymphocytes: 'functional cure?'
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Reported by Jules Levin
International Workshop on HIV & Hepatitis Virus Drug Resistance
5-9 June 2012, Sitges, Spain
Raymond F. Schinazi, PhD, DSc
Frances Winship Walters Professor
Director, Scientific Working Group on Viral Eradication,
Emory University CFAR
Emory Institute for Drug Discovery
rschina@emory.edu
Workshop Report for NATAP by Mark Wainberg:
"........the data suggest that these compounds might interfere with the ability of HIV to achieve latency in a variety of target cell types and that they were active against all of a variety of forms of drug-resistant HIV-1 that were tested...."
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