icon-    folder.gif   Conference Reports for NATAP  
 
  20th Conference on Retroviruses and
Opportunistic Infections
Atlanta, GA March 3 - 6, 2013
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CROI 2013: Comorbidities- Aging/Kidney/Heart/Belly Fat/HCV/Bone/Statins/Frailty
 
 
  Aging

- A Longitudinal Study of the Effects of Ageing and HIV-1 Infection on Cognitive Performance - (04/02/13)

- Follow-up of HIV-Associated Neurocognitive Disorders in the cART Era: the Neuradapt Study - (04/02/13)

- Cardiovascular-related Deaths in HIV-infected Patients between 2000 and 2010, The ANRS EN20 Mortalite 2010 Survey: the 3rd leading cause of death was liver disease 10.8%, non-AIDS cancers 22.1%, AIDS 25%, CVD deaths/sudden deaths 13.6% - (04/02/13)

- The Contribution of Intestinal Epithelial Cell Damage, Microbial Translocation, and HIV Status to an Inflammaging Phenotype - (03/13/13)

- Frailty and Circulating Markers of Inflammation in HIV+ and HIV- Men in the Multicenter AIDS Cohort Study - (03/07/13)

- Age Raises Rate of Dangerous Coronary Artery Plaques in HIV+ But Not HIV- MACS Men - written by Mark Mascolini - (03/05/13)

- Higher MI, ESRD, Cancer Rates With HIV--But Not Necessarily at Younger Age - written by Mark Mascolini - (03/05/13)

- Projecting CVD risks in HIV-infected individuals in the US: competing risks and premature aging - (03/12/13)

- Inflammation, Monocyte Activation in CVD & Non-AIDS Events - (03/12/13)

- HIV-Infected Adults Are at Greater Risk for Myocardial Infarction (MI), End-stage Renal Disease (ESRD), and Non-AIDS-defining Cancers, But Events Occur at Similar Ages Compared to HIV-uninfected Adults (VA) - (03/11/13)

- Subclinical Heart Disease is Greater Among HIV+ vs HIV- & Increases with Age in MACS - (03/11/13)

- Proportion of HIV Deaths Due to Heart Disease Almost Doubles in France From 2000 to 2010 - written by Mark Mascolini - (03/11/13)

- Rise in Heart Disease Risk With Age Slightly Greater With HIV Than in General Population.......[DAD study also shows that reducing risk factors can have a big impact on reducing heart disease] - written by Mark Mascolini - (03/09/13)

- Over 10% in Older HIV Group Fit Alzheimer's Biomarker Risk Profile - written by Mark Mascolini - (03/08/13)

- Longitudinal Association of HIV-associated neurocognitive disorder (HAND) with Frailty in HIV+ Men - (03/08/13)

- Long-Term Efavirenz Use is Associated with Worse Neurocognitive Functioning - (03/07/13)

HCV, Women in WIHS

- Predictors of Mortality among United States Veterans with Human Immunodeficiency Virus and Hepatitis C Virus (HIV/HCV) Co-Infection - (04/01/13)

- Hepatitis C Co-infection and the Risk of Chronic Kidney Disease in HIV-infected Individuals: Does Hepatitis C Viremia Matter? - (04/01/13)

- Impact of Hepatitis Serostatus on Hospitalization Rates and Reasons for Admission in a Multi Center Cohort of Persons Living with HIV in the U.S Multi-Center Cohort of persons Living with HIV in the US - (04/01/13)

- Does persistent hepatitis C viremia lead to advanced liver fibrosis progression early after acute hepatitis C infection in HIV coinfection? - (04/01/13)

Hepatic Fibrosis and Immune Phenotypes Vary by Hepatitis C Viremia in HIV Infection: A Women's Interagency HIV Study.....[from Jules: HCV Viremia Increased Fibrosis/Immune-Dysregulation; HIV Drives Immune Activation but HCV Contributes to Immune Activation] - (03/15/13)

The Effect of Hepatic Fibrosis and HCV viremia on Serum Inflammatory Mediators in HIV Infection - a Women's Interagency HIV Study - (03/16/13)

New HCV Drugs-HCV at CROI - (03/17/13)

BELLY FAT

- Associations Between Regional Fat Deposition and Neurocognitive Function in the Multicenter AIDS Cohort Study - (04/09/13)

- High Grade Liver Steatosis and Cognitive Impairment in HIV+ patients - (04/09/13)

Heart Disease

CROI: Heart Disease/CROI - (03/17/13)

SUBCLINICAL HEART DISEASE in Women & Men

CROI: Noncalcified Coronary Plaque and Macrophage Activation are Increased in HIV-Infected Women - (03/18/13)

CROI: Subclinical Heart Disease is Greater Among HIV+ vs HIV- & Increases with Age in MACS - (03/11/13)....noncalcified plaque in men presented by Wendy Post; young HIV+ men with well-controlled HIV have higher burden of plaque vulnerable to rupture, presented by Steve Grinspoon using CT angiography, the men's study vs women's study below

Increased Coronary Atherosclerotic Plaque Vulnerability by Coronary Computed Tomography Angiography in HIV-Infected Men - (02/11/13)

Soluble Markers of Inflammation & Coagulation, but not T-Cell Activation, Predict Non-AIDS Defining Events During Suppressive Antiretroviral Therapy (ART) - (03/13/13)

Coronary Artery Danger Signals More Common in Young HIV+ Men Than HIV- Men - written by Mark Mascolini - (03/05/13)

Projecting CVD risks in HIV-infected individuals in the US: competing risks and premature aging - (03/12/13)

Kidney

Prevalence of Chronic Kidney Disease Among HIV-infected Adults in Care in the United States Medical Monitoring Project, 2009 - (04/01/13)

Lower Current CD4s--But Not Tenofovir--Predict Advanced CKD/ESRD in D:A:D - written by Mark Mascolini - (03/15/13)....."the strongest identified predictors of advanced CKD/ESRD were traditional risk factors and current CD4 count- hypertension, diabetes, current smoking.

Proteinuria is Associated with Neurocognitive Impairment in HIV Infected Subjects Enrolled in the AIDS Clinical Trials Group (ACTG) Longitudinal Cohort Study (ALLRT) - (03/28/13)

Hepatitis C Co-infection and the Risk of Chronic Kidney Disease in HIV-infected Individuals: Does Hepatitis C Viremia Matter? - (04/01/13)

Cancer

Hodgkin Lymphoma Is Almost As Prevalent As Non-Hodgkin Lymphoma in HIV+ Patients With Sustained Viral Suppression And Limited Immune Deficiency - (04/01/13)

Bone

HIV is an Independent Predictor of Lower Bone Mineral Density in HIV-positive Subjects Compared to HIV-negative Subjects - (04/01/13)

Fracture Among Older and Younger HIV+ Medicare Beneficiaries - (03/28/13)

Peak Bone Mass Lower in Young HIV+ vs HIV- Men--and Bone Structure Abnormal - written by Mark Mascolini - (03/06/13)

Fall Frequency and Associated Factors among Men and Women with or at Risk for HIV Infection - (04/05/13)

A Longitudinal Study of the Effects of Ageing and HIV-1 Infection on Cognitive Performance - (04/02/13)

Follow-up of HIV-Associated Neurocognitive Disorders in the cART Era: the Neuradapt Study - (04/02/13)

Statins

The Effect of Statins on Immune activation and Inflammation in HIV-Infected Subjects on Antiretroviral Therapy: a Randomized Placebo Controlled Trial - (03/19/13)

Statin therapy and mortality in HIV-infected individuals; A Danish nationwide population-based cohort study. - (03/20/13)

Every Year of Statin Therapy Boosts Diabetes Risk 10% in US HIV Cohort - written by Mark Mascolini - (03/20/13)

Is Statin Use Associated with Incident Diabetes Mellitus among Patients in the HIV Outpatient Study (HOPS)? - (03/20/13)

The Kidney at CROI 2013 - Christina M. Wyatt, MD Assistant Professor, Medicine/ Nephrology Mount Sinai School of Medicine New York, NY - (03/21/13)

CROI 2013: Cardiovascular Disease and Co-morbidities in HIV - written by David H. Shepp, MD Associate Professor of Medicine, Hofstra North Shore-LIJ School of Medicine North Shore University Hospital - Manhasset, NY (03/11/13)

Update from 20th CROI: Bones, Vitamin D, Frailty - Todd T. Brown, MD, PhD Association Professor of Medicine and Epidemiology Division of Endocrinology and Metabolism Johns Hopkins University - (04/01/13)

Complications of HIV and its treatment, Impressions from the 20th CROI - Pablo Tebas, MD University of Pennsylvania - (03/20/13)