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Early initiation of antiretroviral therapy for individuals with HIV infection: A systematic review
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from Jules: Although the USA DHHS ART Treatment Guidelines recommend ART for all HIV-infected to reduce risk of disease progression with a slightly lower grade of recommendation of BIII for >500 compared to AII for 350-500, at IAS WHO updated their ART guidelines with a recommendation to treat when CD4s fall below 500 as previously while the previous WHO recommendation, set in 2010, was to offer treatment at 350 CD4 cells/mm3 or less.
IAS: WHO issues new ART HIV recommendations calling for earlier treatment - More Conservative Than HHS ART Guidelines -
IAS: Systemic Review Sees Evidence for Advantage to Starting ART Above 500 CD4s - written by Mark Mascolini - (07/02/13)
Reported by Jules Levin
IAS 2013 June 30-July 3 Kuala Lumpur
Anglemyer AT,1 Rutherford GW,1 Easterbrook PJ,2
Horvath T,1 Vitoria M,2 Doherty M2
1. Global Health Sciences, AIDS Research Institute and Cochrane HIV/AIDS Group,
University of California, San Francisco, San Francisco, California, USA
2. Department of HIV/AIDS, World Health Organization, Geneva, Switzerland
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