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Abdominal Obesity, Inflammation, Immune Activation and Neurocognitive Impairment
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Reported by Jules Levin
CROI 2014 March 3-6 Boston, MA
Fred Sattler1, Jiaxiu He2, Scott Letendre3, Cara Wilson4, Chelsea Sanders3, Robert Heaton3, Ronald Ellis3, Donald Franklin3, Ann Collier5, Christina Marra5,
David Clifford6, Benjamin Gelman7, Justin McArthur8, Susan Morgello9, David Simpson9, Igor Grant3 and J. Allen McCutchan3 for the CHARTER Group
1University of Southern California, Medicine, Los Angeles, CA, 2University of Southern California, Preventive Medicine, Los Angeles, CA, 3University of California San Diego, San Diego, CA, 4University of Colorado, Medicine, Denver, CO, 5University of Washington, Seattle, WA, 6Washington University, St. Louis, MO, 7University of Texas Medical Branch, Galveston, TX, 8Johns Hopkins University, Baltimore, MD, 9Icahn School of Medicine at Mount Sinai, New York, NY
from Jules: the literature is strewn with research in & out of HIV that belly fat is associated with neuro/cognitive impairment. This CHARTER Study finds IL-6(inflammation), waist circumference , as well as lipids contributing, all associated with & neurocognitive impairment (NCI).
again, exercise & good diet are the only proven antidotes for these conditions in addition to keeping CD4s as high as possible, over 1000 CD4 is better, and undetectable viral load.
CROI: Physical Function Impairment on Quality of Life among Persons Aging with HIV Infection - (03/14/14)
CROI: Brisk Walking Improves Inflammatory Markers in cART-Treated Patients - (03/14/14)
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