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The Effect of Calcium and Iron Supplements
on the Pharmacokinetics of Dolutegravir in Healthy Subjects
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Reported by Jules Levin
15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy; May 19-21, 2014; Washington, DC
Ivy Song,1 Julie Borland,2 Niki Arya,1 Brian Wynne,3 Stephen Piscitelli3
1Quantitative Sciences; 2Clinical Pharmacology Science & Study Operations; 3Infectious Disease Medicine Development, GlaxoSmithKline, RTP, NC
15th Intl Wrkshp Clinical Pharm HIV Therapy Calcium and Iron Supplements Lower Dolutegravir Levels When Taken Between Meals - written by Mark Mascolini - (05/20/14)
Product Insert: TIVICAY should be taken 2 hours before or 6 hours after taking cation-containing
antacids or laxatives, sucralfate, oral iron supplements, oral calcium supplements, or buffered medications.
(7.3) http://www.natap.org/2013/HIV/us_tivicay.pdf
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