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A Mechanistic SimCYP Simulation Evaluating Dolutegravir and Efavirenz Pharmacokinetics Following a Switch From Once-daily Efavirenz to Once-daily Dolutegravir
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Reported by Jules Levin
15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy, May 19-21, 2014, Washington, DC
Grant Generaux,1 Ivy Song,2 Gary Bowers,1 and Stephen Piscitelli3
1Drug Metabolism and Pharmacokinetics; 2Clinical Pharmacology Modeling and Simulation;
3Infectious Disease Medicine Discovery and Development, GlaxoSmithKline, Research Triangle Park, NC
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