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A Single Dose of RG-101, a GalNAc-Conjugated Oligonucleotide Targeting miR-122, Results in Undetectable HCV RNA Levels in Chronic Hepatitis C Patients at Week 28 of Follow-up
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Reported by Jules Levin
AASLD 2015 Nov 13-17 San Francisco
M.H. van der Ree 1, J.M.L. de Vree 2, F. Stelma 1, S.B. Willemse 1, M. van der Valk 1, S. Rietdijk 1,3, R. Molenkamp 4, J. Schinkel 4, S. Hadi 5, M. Harbers 5, A. van Vliet 5, J. Udo de Haes 5, P. Grint 6, S. Neben 6, N. Gibson 6 and H.W. Reesink 1
1. Dep. of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
2. Dep. of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands
3. Dep. of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
4. Dep. of Medical Microbiology, Clinical Virology Laboratory, Academic Medical Center, Amsterdam, The Netherlands
5. PRA Healthsciences, Zuidlaren, The Netherlands
6. Regulus Therapeutics, San Diego, CA, USA
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