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Hepatitis C Cure Leads to a Durable Decrease in Liver Stiffness..... "cirrhosis persisted in 58%"
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"There is an urgent need to identify and treat patients so that permanent liver damage can be avoided"
from Jules: in other words these 2 studies both show that in patients with advanced HCV disease despite achieving an SVR cirrhosis persisted in a significant percent of patients, as the authors it is urgent to identify & treat patients rely before liver damage occurs, to avoid permanent liver damage.
Reported by Jules Levin
AAS:D 2015 Nov 13-17 San Francisco
Sweta Chekuri, Jillian Nickerson, Roberta Sefcik, Kian Bichoupan,
David DelBello, Douglas Dieterich, Ponni Perumalswami, Andrea Branch
Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY.
AASLD: Regression of Advanced Fibrosis or Cirrhosis Measured by Elastography in Patients with Chronic Hepatitis C who Achieve Sustained Virologic Response after Treatment for HCV - (12/01/15) AND THIS STUDY found ONLY 55% with cirrhosis REGRESSED, 45% had NO CHANGE, a small percentage worsened. Among F3/4 at baseline 69% regressed, 17% worsened, 15% were unchanged
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