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Improved Safety and Efficacy of TAF vs TDF
Single-Tablet Regimen in HIV-1 Treatment-Naïve Women Through Week 48
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Reported by Jules Levin
EACS 2015 Oct 21-24 Barcelona, Spain - 15th European AIDS Conference
Chloe Orkin,1 Ellen Koenig,2 Amanda Clarke,3 Melanie Thompson,4 Manuela Doroana,5 Daniel Podzamczer,6 Juan Berenguer,7 Bonaventura Clotet,8 Adriano Lazzarin,9 Manuel Crespo,10 Joseph M. Custodio,11 Susan Guo,11 Hui Wang,11
Christian Callebaut,11 Devi SenGupta,11 Moupali Das,11 Marshall Fordyce11
1Royal London Hospital, London, UK; 2Instituto Dominicano de Estudios Virologicos, Santo Domingo, Dominican Republic; 3Royal Sussex County Hospital, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK; 4AIDS Research Consortium of Atlanta, Georgia, USA; 5Hospital de Santa Maria, Lisbon, Portugal; 6Bellvitge Institute for Biomedical Research (IDIBELL), Bellvitge University Hospital, Barcelona, Spain; 7Hospital General Universitario Gregorio Marañón, Madrid, Spain; 8Institut de Recerca de la Sida IrsiCaixa, Hospital Germans Trias i Pujol, Barcelona, Spain; 9San Raffaele Scientific Institute, Milan, Italy; 10Vall d'Hebrón Hospital, Barcelona, Spain; 11Gilead Sciences, Inc., Foster City, California, USA
References
1. d'Arminio Monforte A, et al. AIDS 2010;24:1091-4; 2. Firnhaber C, et al. HIV Clin Trials 2015;16:89-99; 3. UNAIDS Global Report. http://www.unaids.org/en/resources/documents/2014; 4. Sax PE, et al. Lancet 2015;385:2606-15;
5. Babusis D, et al. Mol Pharm 2013;10:459-66; 6. Birkus G, et al. Antimicrob Agents Chemother 2007;51:543-50; 7. Lee W, et al. Antimicrob Agents Chemother 2005;49:1898-906; 8. Ruane P, et al. J Acquir Immune Defic Syndr 2013;63:449-5; 9. Sax P, et al. J Acquir Immune Defic Syndr 2014;67:52-8.
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