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Switch to maraviroc (MVC) + darunavir/ritonavir (DRV/r) in virologically suppressed patients with R5-tropic virus is associated with an excess of virological failures: 48 weeks results of the GUSTA study
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Reported by Jules Levin
EACS 2015 Oct 21-24 Barcelona, Spain - 15th European AIDS Conference
B. Rossetti1,2, R. Gagliardini2, G. Meini3, G. Sterrantino4, V. Colangeli5, M.C. Re6, A. Latini7, M. Colafigli7, F. Vignale8, S. Rusconi9, V. Micheli10, A. Di Biagio11, G. Orofino12, V. Ghisetti13, A. Fantauzzi14, V. Vullo14, P. Grima15,
D. Francisci16, C. Mastroianni17, A. Antinori18, S. Lamonica2, A.D'Avino2, M. Zazzi3, S. Di Giambenedetto2, A. De Luca1, on behalf of GUSTA study group
1University Infectious Diseases Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy, 2Clinic of Infectious Diseases, Catholic University of Sacred Heart, Roma, Italy, 3Department of Medical Biotechnology, University of Siena, Siena,
Italy, 4Clinic of Infectious Diseases, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy, 5Clinic of Infectious Diseases, Azienda Ospedaliera Universitaria S.Orsola Malpighi, Bologna, Bologna, Italy, 6Microbiology, Azienda Ospedaliera
Universitaria S.Orsola Malpighi, Bologna, Italy, 7Infectious Dermatology and Allergology IRCCS IFO, Roma, Italy, 8Clinic of Infectious Diseases, G. D'Annunzio University, Chieti, Italy, 9Infectious and Tropical Diseases Unit, L. Sacco Hospital, University of Milano, Milano, Italy, 10Microbiology and Virology Laboratory, L. Sacco Hospital, Milano, Italy, 11Infectious Diseases Unit, IRCCS S. Martino-IST, Genova, Italy, 12Infectious Diseases Unit A, Amedeo di Savoia Hospital, Torino, Italy, 13Microbiology and Virology Laboratory, Amedeo di Savoia Hospital, Torino, Italy, 14Department of Clinical Medicine, Sapienza University of Rome, Roma, Italy, 15Division of Infectious Diseases, S.Caterina Novella Hospital, Galatina, Italy, 16Clinic of Infectious Diseases, University of Perugia, Perugia, Italy, 17Infectious Disease Unit, SM Goretti Hospital, Sapienza University, Latina, Italy, 18Infectious Diseases Unit, IRCCS L. Spallanzani, Roma, Italy
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