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Advanced Fibrosis is Common in Individuals whose Hepatitis C Has Not Been Diagnosed: Results from the National Health and Nutrition Examination Survey 2001-2012
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Reported by Jules Levin
EASL 2015 April 22-26 Vienna Austria
Prowpanga Udompap, Ajitha Mannalithara, Nae---Yun Heo, W. Ray Kim
Division of Gastroenterology and Hepatology Stanford University, Stanford, United States
CROI/2015: The Burden of Liver Disease among Persons with Hepatitis C in the United States...."the need is urgent to identify HCV-infected persons & link them to management & care" screening - (03/06/15)......CDC/Quest analysis using commercial testing data using FIB-4...."About one-half of HCV-infected persons born from 1945-1965 had severe fibrosis or cirrhosis as measured by FIB-4 scoring (but of all infected persons combined about 40% had severe fibrosis or cirrhosis.....among older persons <1945....74% had severe fibrosis or cirrhosis...11% in younger persons >1965).....However, the measurement of the total Burden in the population of infected persons in the US with advanced fibrosis and compensated cirrhosis is unknown because we do not conduct routine HCV screening [from Jules: which is why we need widespread HCV screening/linkage to care programs, there is little federal funding to support this] .......Of all persons with severe fibrosis or cirrhosis, 81% were born from 1945-1965 .....Proportions were consistent over time
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