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Efficacy and safety of Paritaprevir/r/Ombitasvir/Dasabuvir ±Ribavirin in GT1 HCV infected patients treated in real life settings (AMBER study - interim analysis)
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Reported by Jules Levin
Viral Hepatitis Congress Sept 10-12
Frankfurt, Germany
Abbvie GT1b GIFT-1/TURQUOISE-III - (07/13/15)
Approximately 160 million people worldwide are infected with HCV.2 Genotype 1 is the most common type of HCV genotype, accounting for 60 percent of cases worldwide3 and in Europe, the most prevalent genotype is 1b (47 percent).
Abbvie AMBER Press Release-
http://abbvie.mediaroom.com/2015-09-11-Ongoing-Real-World-Study-Reports-High-Sustained-Viral-Response-Rates-with-VIEKIRAX-ombitasvir-paritaprevir-ritonavir-tablets-EXVIERA-dasabuvir-tablets-in-Genotype-1-Hepatitis-C-Patients
100 percent SVR(12) rate achieved with VIEKIRAX®
(ombitasvir/paritaprevir/ritonavir tablets) + EXVIERA® (dasabuvir tablets) without ribavirin.......http://abbvie.mediaroom.com/2015-06-24-AbbVie-Announces-New-Phase-3b-Results-in-Genotype-1b-Chronic-Hepatitis-C-Patients-with-Compensated-Liver-Cirrhosis
Robert Flisiak1, Ewa Janczewska2, Marta Wawrzynowicz-Syczewska3, Alicja Wiercinska-Drapalo4, Dorota Zarebska-Michaluk5, Beata Bolewska6, Katarzyna Fleischer-Stepniewska7, Krzysztof Tomasiewicz8, Karolina Rostkowska9, Kornelia Karwowska10, Anna Piekarska11, Olga Tronina12, Arkadiusz Pisula2, Mariusz Lucejko1, Ewa Karpinska3, Khalil Nazzal4, Wieslaw Kryczka5, Iwona Mozer-Lisewska6, Brygida Knysz7.
1.Klinika Chorob Zakaznych i Hepatologii UM, Bialystok, Poland
2.ID Clinic, Myslowice, Poland
3.Klinika Chorob Zakaznych, Hepatologii i Transplantacji Watroby PUM, Szczecin, Poland
4.Klinika Chorob Zakaznych, Tropikalnych i Hepatologii UM, Warsaw, Poland
5.Klinika Chorob Zakaznych WSZ i UJK, Kielce, Poland
6.Katedra i Klinika Chorob Zakaznych UM, Poznan, Poland
7.Katedra i Klinika Chorob Zakaznych, Chorob Watroby i Nabytych Niedoborow Odpornosciowych, UMED, Wroclaw, Poland
8.Katedra i Klinika Chorob Zakaznych UM, Lublin, Poland
9.I Oddzial Zakazny WSS im. Gromkowskiego, Wroclaw, Poland
10.Katedra i Klinika Chorob Zakaznych i Hepatologii CM UMK, Bydgoszcz, Poland
11.Klinika Chorob Zakaznych i Hepatologii UM, Lodz, Poland
12.Klinika Medycyny Transplantacyjnej i Nefrologii UM, Warsaw, Poland
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