......aerobic exercise improved cognition, increased brain volume.....a 50 yr old HIV+ who exercises has same brain volume as sedentary 40 yr old HIV+, exercise prevents decline with aging.....this study quantifies effects of exercise on brain health through neuroimaging......Subjects underwent neuroimaging and neuropsychological evaluations.....A cross-sectional cohort of 70 HIV+ individuals (19-82 age range) had neuropsychological performance (NP) testing, neuroimaging, and completed an extensive self-report AE questionnaire that split the cohort into physically active (n=22) and sedentary (n=48) groups..... from Jules: real-world exercise/diet intervention studies are needed