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Tenofovir and the Incidence of Hepatocellular Carcinoma in HIV/HBV-coinfected Persons
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Reported by Jules Levin
CROI 2016 Feb 22-24 Boston
Wandeler G1,2, Kraus D1,2, Reiss P3,4,8, Peters L5, Dabis F6, Fehr J7, van der Valk M8, Gjaerde L5, Bonnet F6,9, Rauch A1 for the Swiss HIV Cohort Study, Athena Observational Cohort Study, EuroSIDA and ANRS CO3 Aquitaine Cohort 1Department of Infectious Diseases, Bern University Hospital, University of Bern, Switzerland, 2Institute of Social and Preventive Medicine, University of Bern, Switzerland, 3HIV Monitoring Foundation, Amsterdam, the Netherlands, 4Department of Global Health, Academic Medical Center, Amsterdam, the Netherlands, 5Copenhagen HIV Programme, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, 6ISPED, Universite Bordeaux, Centre INSERM U1219- Epidemiologie-Biostatistique, France, 7Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Switzerland, 8Department of Infectious Diseases, Academic Medical Center (AMC), Amsterdam, the Netherlands, 9CHU Bordeaux, Service de Medecine Interne et Maladies Infectieuses, Bordeaux, France
Over 32,673 patient-years (py), 60 individuals (1.7%) developed an HCC, resulting in an overall incidence of 1.84 per 1,000 py (95% confidence interval [CI] 1.40-2.36).
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