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Sustained Virologic Response Predicts Fibrosis Regression Measured by FibroTest in HCV-Infected Patients - 'Earliest Treatment Provides Most Regression' ***
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from Jules: of note TREATING VERY EARLY PROVIDES BEST OUTCOMES, once patient gets to F2 fibrosis regression gets increasingly less likely increasing risk for cancer/HCC
Reported by Jules Levin
EASL 2016 April 14-17 Barcelona
Xavier Forns1, Tania M Welzel2, Eric Cohen3, Ira M Jacobson4, Mitchell Davis5, Robert Reindollar6, Bonnie Hu3, Douglas E Dylla3, Jeff rey V Enejosa3, Roger Trinh3, Mark S Sulkowski7
1Liver Unit, Hospital Clinic, CIBEREHD, IDIBAPS, Barcelona, Spain; 2JW Goethe University, Frankfurt, Germany; 3AbbVie Inc., North Chicago, Illinois, United States; 4Mount Sinai Beth Israel, New York, New York, United States; 5Digesti ve Care-South Florida Center of Gastroenterology, Wellington, Florida, United States; 6Piedmont Healthcare/Carolinas Center for Liver Disease, Statesville, North Carolina, United States; 7Johns Hopkins University, Balti more, Maryland, United States
from Jules: SVR FIBROSIS REGRESSION BEST WITH EARLY TREATMENT at F0-F1 - very important study finding 96% of patients with F0-1 achieve at least fibrosis does not worsen, while for F2 only 69% achieve improved fibrosis from F2 to F0-1 & 16%remain at F2, for F3 only 46% improve to F0-F1 while 5% worsen to F4 & 30% remain at F3, BUT for those treated with F4 score 49% do not improve.
Reported by Jules Levin
EASL 2016 April 14-17 Barcelona
Xavier Forns1, Tania M Welzel2, Eric Cohen3, Ira M Jacobson4, Mitchell Davis5, Robert Reindollar6, Bonnie Hu3, Douglas E Dylla3, Jeff rey V Enejosa3, Roger Trinh3, Mark S Sulkowski7
1Liver Unit, Hospital Clinic, CIBEREHD, IDIBAPS, Barcelona, Spain; 2JW Goethe University, Frankfurt, Germany; 3AbbVie Inc., North Chicago, Illinois, United States; 4Mount Sinai Beth Israel, New York, New York, United States; 5Digesti ve Care-South Florida Center of Gastroenterology, Wellington, Florida, United States; 6Piedmont Healthcare/Carolinas Center for Liver Disease, Statesville, North Carolina, United States; 7Johns Hopkins University, Balti more, Maryland, United States
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