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The Effect of Sustained Virologic Response on Cerebral Metabolism and
Neurocognition in Patients With Chronic Genotype 1 HCV Infection
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Reported by Jules Levin
EASL 206 April 14-17 Barcelona
Michael P. Curry,1 Nancy P. Moczynski,1 Hong Liu,2 Luisa M. Stamm,2 Chohee Yun,2 Diana M. Brainard,2 John G. McHutchison,2 David Alsop,1 Nezam H. Afdhal1
1Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; 2Gilead Sciences, Inc., Foster City, California, USA
Memory T score = visuospatial memory immediate total T score + visuospatial memory delayed T score + verbal memory total T score + verbal memory delayed T score;
Attention scaled score = forward digit span scaled score + backward digit span scaled score + symbol span total scaled score; Executive processing speed score = symbol search total scaled score + (90 - Trail A total raw score); Executive conceptual shifting and initiation score = Trail B raw score + color word interference score (time) + color word interference/shifting score (time) + (90 - age and education adjusted raw score); Motor score = dominant hand fine motor speed (time) + nondominant hand fine motor speed (time). Error bars represent standard deviations.
Reference
1. Hilsabeck RC, et al. Hepatol 2002;35:440-6;
2. Weissenborn K, et al. J Hepatol 2004;41:845-51;
3. Alsop D, et al. Hepatol 2014;60(Suppl 1):221A;
4. Byrnes V, et al. J Hepatol 2012;56:549-56.
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