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TREATMENT OF CHRONICALLY HBV-INFECTED CHIMPANZEES WITH RNA INTERFERENCE THERAPEUTIC ARC-520 LED TO POTENT REDUCTION OF VIRAL MRNA, DNA AND PROTEINS WITHOUT OBSERVED DRUG RESISTANCE
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Reported by Jules Levin
EASL 2016 April 14-27 Barcelona
Zhao Xu* 1, Deborah Chavez2, Bernadette Guerra2, Margaret Littlejohn3, Ryan Peterson1, Stephen Locarnini3, Robert Gish4, Christopher Anzalone1, Steven Kanner1, Jason Goetzmann5, Robert Lanford2, David Lewis1, Christine Wooddell1
1Arrowhead Research Corporation, Madison, 2Texas Biomedical Research Institute, San Antonio, United States, 3Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia, 4Liver Transplant Program, Stanford University Medical Center, San Diego, 5New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, United States
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