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Frailty in HIV+ in Italy....average age only 49 but 12% frail, 28% pre-frail, 33% some measure of depression, 51% cognitive impairment.
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Reported by Jules Levin
Glasgow HIV Oct 2016
Vita Serena1* , Lichtner Miriam 2 , Rossi Raffaella 1 , Pozze:o Irene2, Tosato Cecilia1, Marocco Raffaella2, Zuccalà Paola1, Mascia Claudia1,Campagna Michela1, d'E:orre Gabriella1, Turriziani Ombre:a1, Falasca Francesca1, Ajassa Camilla1, Mastroianni Claudio Maria2and Vullo Vincenzo1
1Sapienza University of Rome,
2Sapienza University of Rome, Polo PonPno
*serena.vita@uniroma1.it
Although our study population was asymptomatic and without known organ diseases, we found a high prevalence of pre frail and frail patients with cognitive impairment and depression. Factors associated to frailty were smokers status, HCV coinfection, depression, cognitive impairment, PI-based therapy and an increased inflammatory milieu in terms of sCD14.
Multivariate analysis with a larger sample is needed to confirm these results.
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