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Correlates for levels of self-reported PrEP adherence among
Black men who have sex with men in 3 U.S. cities
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Reported by Jules Levin
Durban 2016 July 18-22
Results: Among the total 226 enrolled participants, 178 (79%) participants initiated PrEP. Proportions of self-reported high PrEP adherence (≥90%) ranged between 62% and 71%, while self-reported low PrEP adherence (< 50%) ranged between 13% and 19% during weeks 13 through 52. High adherence is associated with age ≥25, higher education, full time employment, no poly drug use and having a primary partner. Conversely, low adherence is associated with younger age, less education, non-fulltime employment, poly drug use, and no primary partner. Adjusted analysis shows that having a primary partner and no poly drug are highly associated with high adherence, whereas converse is true for low adherence.
Conclusions: Understanding the contextual factors that support and impede adherence (Figure 1) and targeting these in comprehensive intervention packages may maximize PrEP adherence and minimize lower adherence for BMSM. Our data support consideration of the need for addressing these factors as core elements for BMSM.
Presenter
Darrell Wheeler
Authors
D. Wheeler1, S. Fields2, L. Nelson3, L. Hightow-Weidman4, M. Magnus5, S. Shoptaw6, G. Beauchamp7, L. Emel8, E. Piwowar-Manning9, Y. Chen7, P. Watkins10, K. Mayer11,12, HPTN073 Study Team
Institutions
1State University of New York at Albany, Social Welfare, Albany, United States, 2Charles Drew University, Nursing, Los Angeles, United States, 3University of Rochester, Nursing, Rochester, United States, 4University of North Carolina, Chapel Hill, United States, 5George Washington University, Washington, United States, 6University of California Los Angeles, Los Angeles, United States, 7Statistical Center for HIV/AIDS Research & Prevention (SCHARP), Seattle, United States, 8Fred Hutchinson Cancer Research Center, Seattle, United States, 9Johns Hopkins University, Baltimore, United States, 10FHI 360, Durham, United States, 11The Fenway Institute, Boston, United States, 12Harvard University, Cambridge, United States
Background: HPTN 073 Study assessed the initiation, acceptability, safety, and feasibility PrEP for Black men who have sex with men (BMSM) in three US cities. Upon the PrEP initiation, levels of PrEP use were monitored using self-reported adherence.
Methods: HPTN 073 Study enrolled 226 HIV-uninfected BMSM in three US cities(
Los Angeles, CA, Washington DC, and Chapel Hill, NC, August 2013 and September 2014). All study participants were offered once daily oral FTC/TDF and client centered care coordination, and were followed for 12 months, with scheduled clinical visits every 13 weeks.
Results: Among the total 226 enrolled participants, 178 (79%) participants initiated PrEP. Proportions of self-reported high PrEP adherence (≥90%) ranged between 62% and 71%, while self-reported low PrEP adherence (< 50%) ranged between 13% and 19% during weeks 13 through 52. High adherence is associated with age ≥25, higher education, full time employment, no poly drug use and having a primary partner. Conversely, low adherence is associated with younger age, less education, non-fulltime employment, poly drug use, and no primary partner. Adjusted analysis shows that having a primary partner and no poly drug are highly associated with high adherence, whereas converse is true for low adherence.
Conclusions: Understanding the contextual factors that support and impede adherence (Figure 1) and targeting these in comprehensive intervention packages may maximize PrEP adherence and minimize lower adherence for BMSM. Our data support consideration of the need for addressing these factors as core elements for BMSM.
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