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Clinical Pharmacology of the Unboosted HIV Integrase Strand Transfer Inhibitor (INSTI) Bictegravir (BIC)
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Reported by Jules Levin
CROI 2017 Feb 14-17 Seattle, WA
WEBCAST: http://www.croiwebcasts.org/console/player/33377?mediaType=slideVideo&
Heather Zhang, Joseph M. Custodio, Xuelian Wei, Hui Wang, Amanda Vu, John Ling, Hal Martin, Erin Quirk, Brian P. Kearney
Gilead Sciences, Inc., Foster City, CA
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Gilead Presents Preliminary Data on Bictegravir, an Investigational Integrase Strand Transfer Inhibitor for the Treatment of HIV....http://www.natap.org/2016/HIV/062016_02.htm
Discovery of Bictegravir (GS-9883), a Novel, Unboosted, Once-Daily HIV-1 Integrase Strand Transfer Inhibitor (INSTI) with Improved Pharmacokinetics and In Vitro Resistance Profile....http://www.natap.org/2016/HIV/062016_05.htm
Bictegravir (GS-9883), a Novel HIV-1 Integrase Strand Transfer Inhibitor (INSTI) with Optimized In Vitro Resistance Profile....http://www.natap.org/2016/HIV/062016_03.htm
Novel Integrase Strand Transfer Inhibitor Bictegravir 10 Day Monotherapy in HIV-1-Infected Patients....http://www.natap.org/2016/HIV/062016_01.htm
Antiviral Activity of Bictegravir (GS-9883), a Potent Next Generation HIV-1 Integrase Strand Transfer Inhibitor....http://www.natap.org/2016/HIV/062016_04.htm
Potent Activity of Bictegravir (BIC; GS-9883), a Novel Unboosted HIV-1 Integrase Strand
Transfer Inhibitor (INSTI), Against Patient Isolates with INSTI-Resistance [2].....http://www.natap.org/2016/HIV/062316_01.htm
ASM/ICAAC: Potent Activity of Bictegravir (BIC; GS-9883), a Novel Unboosted HIV-1 Integrase Strand Transfer Inhibitor (INSTI), Against Patient Isolates with INSTI-Resistance....http://www.natap.org/2016/HIV/062316_02.htm
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