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In Vitro and In Vivo Characterization of the Selective Toll-Like Receptor 8 Agonist GS-9688
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Reported by Jules Levin
EASL 2017 Amsterdam Netherlands
Stephane Daffis, Dhivya Ramakrishnan, Congrong Niu, Jim Zheng, Rex Santos, Michael R. Mish, Gregory Chin, Vangelis Aktoudianakis, Sammy Metobo,
Hyung-Jung Pyun, Helen Yu, Gary Lee, Adam Palazzo, Christian Frey, Stefan Pflanz, William E. Delaney IV, Simon P. Fletcher, Richard L. Mackman
Gilead Sciences, Inc., Foster City, California, USA
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References
1. Du J, et al. Vaccine 2010;28:6273-81; 2. Isorce N, et al. Antiviral Res 2016;130:36-45; 3. Jo J, et al. PLoS Pathog 2014;10:e1004210; 4. Lu H, et al. Clin Cancer Res 2012;18:499-509; 5. Schurich A, et al. PLoS Pathog 2013;9:e1003208.
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