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In Vitro and In Vivo Characterization of the Selective Toll-Like Receptor 8 Agonist GS-9688
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Reported by Jules Levin
EASL 2017 Amsterdam Netherlands
Stephane Daffis, Dhivya Ramakrishnan, Congrong Niu, Jim Zheng, Rex Santos, Michael R. Mish, Gregory Chin, Vangelis Aktoudianakis, Sammy Metobo,
Hyung-Jung Pyun, Helen Yu, Gary Lee, Adam Palazzo, Christian Frey, Stefan Pflanz, William E. Delaney IV, Simon P. Fletcher, Richard L. Mackman
Gilead Sciences, Inc., Foster City, California, USA
References
1. Du J, et al. Vaccine 2010;28:6273-81; 2. Isorce N, et al. Antiviral Res 2016;130:36-45; 3. Jo J, et al. PLoS Pathog 2014;10:e1004210; 4. Lu H, et al. Clin Cancer Res 2012;18:499-509; 5. Schurich A, et al. PLoS Pathog 2013;9:e1003208.
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