![](images/null.gif) |
![](images/null.gif) |
![](images/null.gif) |
|
A Liver-Targeted Acetyl-CoA Carboxylase Inhibitor Reduces
Hepatic Steatosis and Liver Injury in a Murine Model of NASH
|
|
|
Reported by Jules Levin
EASL - International Liver Congress™, 19-23 April 2017, Amsterdam, the Netherlands
Jamie Bates, Robert Brockett, Igor Mikaelian, Ting Wang, Adrian S. Ray, Daniel Tumas, David Breckenridge
Gilead Sciences, Inc., Foster City, California, USA
![EASL1](../images/070317/070317-7/EASL1.gif)
![EASL2](../images/070317/070317-7/EASL2.gif)
![EASL3](../images/070317/070317-7/EASL3.gif)
![EASL4](../images/070317/070317-7/EASL4.gif)
![ACC](../images/070317/070317-7/ACC.gif)
References
1. Abu-Elheiga L, et al. Proc Natl Acad Sci U S A 2005;201:12011-6;
2. Mao J, et al. Proc Natl Acad Sci U S A 2006;103:8552-7;
3. Harriman G, et al. PNAS 2016;113:E1796-805;
4. Lawitz EJ, et al. EASL 2017, abstr LBO-002;
5. Charlton M, et al. Am J Physiol Gastrointest Liver Physiol 2011;301:G825-34;
6. Konietschke F, et al. J Statistical Software 2015;64.
|
|
|
![](images/null.gif) |
![](images/null.gif) |
|
|