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HIV & Sleep Disorders: 100% of HIV+ with cognitive impairment have sleep disorder study reports
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For many years studies report HIV+ HAVE SLEEPING DISORDERS. Cognitive impairment is often unrecognized by a person with HIV.
HIV & Sleep Disturbances - (05/04/12)
High Prevalence of Insomnia in an Outpatient Population With HIV ... www.natap.org/2008/HIV/041108_01.htm
One of the most striking findings in our study was that 100% of patients with cognitive impairment had sleep disturbances.....HIV enters the central nervous ...
"(73%) respondents were classified as having a sleep disturbance....Anxiety, depression, self-reported sleep disturbance, and signs of cognitive impairment as already defined were significant predictors of insomnia..... One of the most striking findings in our study was that 100% of patients with cognitive impairment had sleep disturbances"
"HIV enters the central nervous system (CNS) shortly after initial infection and may involve the brain before onset of any other physical manifestations of the disease (22,23)....CNS infections often lead to hypersomnolence but may also present with insomnia or sleep-wake cycle disruptions"
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"That psychologic morbidity, particularly depression, and insomnia are consistently related has been well-documented (3,56). A significant finding of this review is that in HIV infection, psychologic morbidity is the major contributor to insomnia rather than other factors such as disease progression or antiretroviral therapy..... Insomnia is a well-recognized feature of psychologic morbidity, and given the prevalence of anxiety and depression reported in HIV infection, it is not surprising that psychiatric disorders should be associated with sleep disturbance in this group..... Using the Hospital Anxiety and Depression Scale (49), Rubenstein and Selwyn found an increased prevalence of both depression (32%) and anxiety (55%) in 115 outpatient attenders of an HIV/AIDS clinic (24). Among patients experiencing insomnia, both depression (41% vs. 10%; p <.005) and anxiety (65% vs. 26%; p <.01) were more common, and multivariate analysis found that depression was an independent predictor of insomnia (OR, 1.17; CI, 1.01-1.36)."
http://www.natap.org/2008/HIV/041108_02.htm
HCV Too
"The purpose of this study was to characterize the feature and degree of sleep disturbances in HCV-infected patients without relevant liver disease and to clarify the patients' symptoms. Furthermore we were interested to analyze the relationship between sleep disturbances, neuropsychiatric symptoms and health-related quality of life.......In conclusion, our data showed altered sleep quality in a group of patients with HCV infection associated neuropsychiatric symptoms but only mild liver disease
http://www.natap.org/2014/HCV/022014_01.htm
Double Hit To The Brain.The Aids virus damages the brain in two ways, by not only killing brain cells but by preventing the birth of new cells, United States researchers reported on Wednesday.
The study, published in the journal Cell Stem Cell, helps shed light on a condition known as HIV-associated dementia, which can cause confusion, sleep disturbances and memory loss in people infected with the virus.
According to Stuart Lipton, a professor at the Burnham Institute for Medical Research's Del E. Webb Center for Neuroscience and Aging Research in La Jolla, Calif., antiviral medications do not successfully cross the blood-brain barrier, allowing the HIV virus to stow away in the brain for up to several years, quietly wreaking havoc. The result: HIV-associated dementia, characterized by, among other symptoms, memory loss, blurred vision, concentration deficits, speech difficulties and motor impairments.
http://www.natap.org/2007/HIV/081607_03.htm
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