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Food Insecurity and Frailty among Women Living with or At-risk for HIV in the U.S.
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Reported by Jules Levin
Aging Workshop Oct 2019
Judy Y. Tan1, Edward A. Frongillo, PhD2, Lila Sheira, MPH3, Leah H. Rubin4, Kathryn Anastos, MD5, Daniel Merenstein, MD6, Mardge H. Cohen, MD7, Adaora A. Adimora, MD8, IghovwerhaOfotokun, MD, MSc9, and Sheri D. Weiser, MD, MPH1,41University of California, San Francisco (UCSF), Center for AIDS Prevention Studies, USA2University of South Carolina, Department of Health Promotion, Education, and Behavior, USA3UCSF, Division of HIV, ID and Global Medicine, 4Johns Hopkins University, Departments of Neurology and Epidemiology, USA5Albert Einstein College of Medicine, Departments of Medicine, USA6Georgetown University Medical Center, USA; 7Department of Medicine, Stroger Hospital, USA8University of North Carolina at Chapel Hill, 9School of Medicine, Emory University, USA
at the Aging Workshop:
Frailty, Physical Function Impairment, Comorbidity Burden, and Falls are Predictive of Mortality Among Middle-Aged Adults with HIV - (10/24/19)
85% MEN. Simple measures of physical function, falls, and comorbidity predicted death 8 years later in 351 middle-aged-to-older people with HIV infection [1]. Timed 400-meter walk proved the strongest individual mortality predictor, followed by comorbidities calculated by the VACS Index, and the Short Physical Performance Battery.
Frailty and Aging (worse mortality): The last 10 years of aging research, and next steps. - (01/23/20)
Loneliness & Social Isolation in HIV: Reduces Mental & Physical Health. The "Village Model in HIV study: pilot in San Diego, app" - (01/22/20)
FRAILTY PHENOTYPE IN OLDER VIROLOGICALLY SUPPRESSED PLWH IS STRONGLY CORRELATED WITH SPECIFIC COMORBIDITIES AND TOBACCO USE - (11/01/19)
Our study strongly suggests that comorbidities are the main factors that convey the embrittlement state of older virologically suppressed PLWHIV. This embrittlement state precedes polypathology or disabilities and undermines ones capacity to fight against physical or mental assaults. Efficient medical follow-up focusing on preventing comorbidities especially in individuals with cancer history, could delay frailty as well as its associated adverse outcomes....."Univariate analysis evidenced no association (at p <0.05) of frailty with age, sex, level of studies, tobacco/alcohol or drug use, or HIV-related parameters. On the contrary, significant associations at p <0.05 were found between frailty and BMI, pain scale, social deprivation, professional activity, psychiatric history, falls, rheumatologic history, and having at least 2 comorbidities.
Multivariate analysis confirmed associations of frailty state with BMI (OR = 1.34[1.12-1.22], p = 0.00), pain scale (OR = 1.46 [1.07-1.25], p = 0.004), psychiatric (OR = 7.62 [1.03-2.80], p = 0.044) and rheumatologic history (OR = 7.84 [1.05-2.86], p = 0.040), falls (OR = 8.33 [1.09-3.01], p = 0.034), while revealing associations of frailty with cancer history (OR = 15.03 [1.61-4.92], p = 0.005), tobacco use (OR = 11.52 [1.37-3.97], p = 0.011) and CD4 T cell nadir count less than 200/mm3 (OR = 0.74 [0.11-0.29], p = 0.010)."
10th International Workshop on HIV and Aging
October 10-11, 2019
New York, NY
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