Conference Reports for NATAP
Conference on Retroviruses
and Opportunistic Infections
Seattle, Washington
March 4-7, 2019
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Update on Antiretroviral Drugs and Pregnancy Outcome Including Birth Defects
Lynne M. Mofenson MD
Senior HIV Technical Advisor
Elizabeth Glaser Pediatric AIDS Foundation
WEBCAST:
http://www.croiwebcasts.org/console/player/41144?mediaType=slideVideo&&crd_fl=0&ssmsrq=1554561673549&ctms=5000&csmsrq=5061
CROI 2019 March 4-7 Seattle
Reported by Jules Levin
at CROI 2019
DOLUTEGRAVIR:
ABSENCE OF DEVELOPMENTAL TOXICITY INCLUDING NTDs IN ANIMAL STUDIES
- (03/19/19)
NO INCREASE IN BIRTH DEFECTS IN INFANTS EXPOSED TO INTEGRASE INHIBITORS AT CONCEPTION
- (03/19/19)
Albano Study -
Integrase Inhibitor Exposure and CNS and Neural Tube Defects: Data from the Antiretroviral Pregnancy Registry (APR)
- (03/19/19)
Reports of Neural Tube Defects for 8 ARVs in FDA, WHO, EMA and UK Pharmacovigilance Safety Databases
- (03/19/19)
Khoo DOLPHIN2 Study -
RCT of dolutegravir vs efavirenz-based therapy initiated in late pregnancy: DOLPHIN-2
Evaluation of Neural Tube Defects After Exposure to Raltegravir During Pregnancy
RANDOMIZED TRIAL OF RALTEGRAVIR-ART VS EFAVIRENZ-ART WHEN INITIATED DURING PREGNANCY -
webcast:
http://www.croiwebcasts.org/console/player/41080?mediaType=slideVideo&&crd_fl=0&ssmsrq=1554560336247&ctms=5000&csmsrq=5059