| |
Ageing with HIV: Emerging importance of
chronic comorbidities in patients over 75
|
| |
| |
>75 HIV+ Have 2-3 Times the Rate of Comorbidities Compared to 50-75 HIV+ : Neoplasia rates 22.6% vs 12%; Renal failure 14% vs 4.7%; heart disease(CVD) 20.7% vs 8.5%; diabetes 22.3% vs 9.4%; hypertension 42.3% vs 21.1%; depression 15.1% vs 16.6%; # of comorbidities 4 or more: 14% vs 4.3%; suicide rate 3.2% vs 1.4%
CROI 2016
Reported by Jules Levin
C. Allavena1, C. Bernaud1, S. Lariven2, M.A. Valantin3, T. Ferry4, L. Cuzin5, A. Naqvi6, A. Cabié7, M. Hanf8 and the ! DatAIDS study group 1Infectious Diseases, CHU Hotel-Dieu, Nantes, 2 Infectious Diseases, AP-HP Hopital Bichat-Claude Bernard, Paris, 3 Infectious Diseases, AP-HP Hopital Pitié Salpétriere, Paris, 4 Infectious Diseases, CHU, Lyon, 5 Infectious
Diseases, CHU, Toulouse, 6 Infectious Diseases, CHU de l’Archet, Nice, 7 Infectious Diseases, CHU, Fort de France, 7, CHU Hotel-Dieu, Nantes, France
75% Projected to Be Over 50. 85% of HIV+ projected to Have Cadiovascular Disease in USA, 30% malignancy, 23% diabetes. Care Costs Increase by 40% due to Comobidities
HIV duration of 20 Years in 75 year olds Doubles Multimorbidities & Polypharmacy Rates & This Causes Using HAART with Less Drugs in the Regimen - Silver champions from the GEPPO cohort (GEriatricPatients living with HIV/AIDS): a case control study of people above 75 years of age addressing Multimorbidity Polypharmacy and Antiretrovirals' Prescription in old HIV patients. - (09/16/16)
chronic kidney disease occurred more often in patients with HIV+ for all HIV groups [<10 yrs; 10-20 yrs; >20 yrs] and was 33% vs 7% in HIV+ for more than 20 years; dyslipidemia as well was 76% in HIV+ for more than 20 years vs 46% in HIV-negatives. Of note, HIV+ because of polypharmacy were prescribed HAART regimens containing less drugs. Twice as many HIV+ received statins.
|
|
| |
| |
|
|
|
