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Impact of Coadministration With or Without Food on the 96-Week Efficacy and Safety of TAF in Virally Suppressed Chronic HBV Patients Switched From Tenofovir Disoproxil Fumarate to TAF
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AASLD 202 Nov 11-16 virtual
Reported by Jules Levin
Jia-Horng Kao,1 Wan-Long Chuang,2 Chi-Yi Chen,3 Sang Hoon Ahn,4 Scott Fung,5 Magdy Elkhashab,6 Hie-Won Hann,7 Natarajan Ravendhran,8 Tuan Nguyen,9 Susanna Tan,10 John Flaherty,10 Anuj Gaggar,10 Bing Gao,10 Diana M. Brainard,10 Charles Phan,11 Young-Suk Lim,12 Maria Buti,13 Pietro Lampertico14
1National Taiwan University Hospital, Taipei City, Taiwan; 2Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, Taiwan; 3Chia-Yi Christian Hospital, Chiayi City, Taiwan; 4Severance Hospital, Seoul, Republic of Korea; 5University of Toronto, Ontario, Canada; 6Toronto Liver Centre, Toronto; 7Thomas Jefferson University Hospital, Philadelphia, PA; 8Digestive Disease Associates, Catonsville, MD; 9Tuan Nguyen, M.D., Research & Education, Inc., San Diego, CA; 10Gilead Sciences, Inc., Foster City, CA; 11Memorial Hermann Sugar Land, TX; 12Asan Medical Center, University of Ulsan College of Medicine, Seoul; 13Hospital Universitari Vall d'Hebron, Barcelona, Spain; 14Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
References: 1. Babusis D, et al. Mol Pharm 2013;10:459-66; 2. Lee WA, et al. Antimicrob Agents Chemother 2005;49:1898-906; 3. Murakami E, et al. Antimicrob Agents Chemother 2015;59:3563-9; 4. Agarwal K, et al. J Hepatol 2015;62:533-40; 5. Agarwal K, et al. J Hepatol 2018;68:672-81; 6. Lampertico P, et al. EASL 2020, abstr 91; 7. Lampertico P, et al. Lancet Gastroenterol Hepatol 2020;5:441-53; 8. Terrault NA, et al. Hepatology 2018;67:1560-99.
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