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  Conference on Retroviruses
and Opportunistic Infections
Boston USA
March 8-11, 2020
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Baseline and Acquired Comorbidities in Patients Initiating ART in the HOPS, 2008-2018
  "with advancing age PLWH [>50] experience increasing burden of chronic comorbiities" suggesting accelerated or perhaps accentuated gang among HIV+, still controversial. Jules
CROI 2020
Reported by Jules Levin
E Tedaldi1, C Armon2, J LI3, G Simoncini1, FJ Palella Jr4, S Purinton2, K Buchacz3, for the HIV Outpatient Study (HOPS) Investigator
1Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA; 2Cerner Corp, Kansas City, MO, USA; 3Centers for Disease Control and Prevention, Atlanta, GA, USA; 4Northwestern University Feinberg School of Medicine, Chicago, IL, USA
"depression was more likely to occur among females"
"Females were more likely than males to have obesity (Rate Ratio [RR] 2.02, 95% Confidence Interval [95%CI]: 1.71-2.39), diabetes (RR 2.00, 95%CI: 1.43-2.80), hepatitis-C (RR 1.74, 95%CI: 1.23-2.46), depression (RR 1.40, 95%CI 1.23-1.59), and psychosis (RR 2.09, 95%CI: 1.08-4.05) (Figure 2)."
- among >50 at end of observation: 93% any comorbidity; hypertension: 75%; CVD 33%; kidney disease 30%; diabetes 20%; psych diagnosis 55%; depression 40%; anxiety 20%......cancers 2% to 2.8% BUT among >50s caner was almost 20%; lung disease also 20% among >50 yr olds