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Association of FIB-4 score with Major Cardiovascular Events (MACE) in real-world populations diagnosed
with NASH or NAFLD in US Clinical Practice
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EASL 2020 Aug 27-29 virtual
Reported by Jules Levin
Michelle Lai1, Jeremy Broestl2, Andrew Frick2, Richard Haubrich3, Bruce Koch3, Scott Milligan2, Macky Natha3, Zobair Younossi4,5, and Nezam Afdhal1
1Beth Israel Deaconess Medical Center, 2Trio Health Analytics, 3Gilead Sciences, Inc., 4Center for Liver Diseases, Department of Medicine, Inova Fairfax Hospital, Falls Church, VA, and 5Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, VA
"Patients with NAFLD have higher incidence of cardiovascular disease (CVD) which is
considered the most common cause of mortality in these patients
In patients diagnosed with NASH/NAFLD, high FIB4 scores are a major independent indicator
of risk of development of MACE during follow-up"
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