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HBV pgRNA and DNA both rebound immediately following discontinuation of the core inhibitor vebicorvir despite continued NrtI treatment in patients with HBeAg positive chronic hepatitis B virus infection: findings from a phase 2 open-label study
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AASLD 2021 Nov 12-15
Man-Fung Yuen1, Xiaoli Ma2, Tarek I Hassanein3, Paul Yien Kwo4, Julie Ma5, Lewyn Li5, Katie Kitrinos5, Steven J Knox5, Luisa M Stamm5, Ho Bae6, Mark S Sulkowski7, Magdy Elkhashab8, Kosh Agarwal9
1Department of Medicine, The University of Hong Kong, Hong Kong; 2Office of Xiaoli Ma, Philadelphia, PA, USA; 3Southern California Research Center, Coronado, CA, USA; 4Division of Gastroenterology and Hepatology, Stanford University Medical Center, Stanford, CA, USA; 5Assembly Biosciences, Inc, South San Francisco, CA, USA; 6St. Vincent Medical Center, Asian Pacific Liver Center, Los Angeles, CA, USA; 7Johns Hopkins School of Medicine, Baltimore, MD, USA; 8Toronto Liver Centre, Toronto, ON, Canada; 9Institute of Liver Studies, King's College Hospital, London, UK
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