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Life Expectancy & Comorbidities: mental & physical comorbidities,
social determinants of health, lifestyle, trauma, social isolation
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Contributions of traditional and HIV-related risk factors on non-AIDS-defining cancer, myocardial infarction, and end-stage liver and renal diseases in adults with HIV in the USA and Canada: a collaboration of cohort studies.....The objective of this study was to estimate the population attributable fractions (PAFs) of preventable or modifiable HIV-related and traditional risk factors for non-AIDS-defining cancers, myocardial infarction, end-stage liver disease, and end-stage renal disease outcomes.....Preventing smoking would avoid 24% (95% CI 13-35) of these cancers and 37% (7-66) of the myocardial infarctions. Preventing elevated total cholesterol and hypertension would avoid the greatest proportion of myocardial infarctions: 44% (30-58) for cholesterol and 42% (28-56) for hypertension. For liver disease, the PAF was greatest for hepatitis C infection (33%; 95% CI 17-48). For renal disease, the PAF was greatest for hypertension (39%; 26-51) followed by elevated total cholesterol (22%; 13-31), detectable HIV RNA (19; 9-31), and low CD4 cell count (13%; 4-21). Lancet HIV https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(18)30295-9/fulltext
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At CROI 2018
LIFE EXPECTANCY IN KEY POPULATIONS OF ADULTS WITH HIV IN THE US AND CANADA (ABSTRACT 903)
Keri N Althoff
Johns Hopkins University, Baltimore, MD, USA
http://www.croiwebcasts.org/console/player/37241?mediaType=slideVideo&
Life expectancy lower for women vs white MSM & lower for white women vs black women.
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Life Extectancy, Mental Comorbidities, Inflammation, /Anti-Inflammatories Drug Research - Life Expectancy Lags in Some HIV Groups: Black MSM, Drug Injectors, HCV+ (03/26/18) This symposium on Life Expectancy at CROI 2018 included several speakers discussing numerous factors.
Here I bring you back to CROI 2018 where Keri Althoff discusses the increasing numbers of comorbidities PLWH are experiencing globally & in the USA and discusses the impact of mental health disorders of PLWH and other factors.
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