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Deeper virologic suppression with the addition of vebicorvir, a first-generation hepatitis B core inhibitor, to entecavir correlates with reduced inflammation and fibrosis-4 index in treatment-naïve patients with HBeAg positive chronic hepatitis B
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EASL 2022 June 22-26 London
Mark S Sulkowski1, Scott K Fung2, Xiaoli Ma3, Tuan T Nguyen4, Eugene R Schiff5, Hie-Won L Hann6, Douglas T Dieterich7, Ronald Nahass8, James S Park9, Sing Chan10, Steven-Huy B Han11, Edward J Gane12, Michael Bennett13, Ran Yan14, Jieming Liu14, Julie Ma14, Steven J Knox14, Luisa M Stamm14,
Maurizio Bonacini15, Ira M Jacobson9, Walid S Ayoub16, Frank Weilert17, Natarajan Ravendhran18, Alnoor Ramji19, Paul Yien Kwo20, Magdy Elkhashab21, Tarek Hassanein22, Ho S Bae23, Jacob P Lalezari15, Kosh Agarwal24, Man-Fung Yuen25
1Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2University of Toronto, Toronto, ON, Canada; 3Office of Xiaoli Ma, Philadelphia, PA, USA; 4T Nguyen Research and Education, Inc., San Diego, CA, USA; 5Schiff Center for Liver Diseases, University of Miami School of Medicine, Miami, FL, USA; 6Thomas Jefferson University Hospital, Philadelphia, PA, USA; 7Department of Medicine, Division of Liver Diseases, Icahn School of Medicine, Mount Sinai Hospital, New York, NY, USA; 8ID Care, Hillsborough, NJ, USA; 9NYU Langone Health, New York, NY, USA; 10Sing Chan, MD, New York, NY, USA; 11Pfleger Liver Institute, University of California, Los Angeles, CA, USA; 12New Zealand Clinical Studies, Auckland, New Zealand; 13Medical Associates Research Group, San Diego, CA, USA; 14Assembly Biosciences, South San Francisco, CA, USA; 15Quest Clinical Research, San Francisco, CA, USA; 16Cedars-Sinai Medical Center, Los Angeles, CA, USA; 17Waikato Hospital, Hamilton, New Zealand; 18Digestive Disease Associates, Catonsville, MD, USA; 19Gastrointestinal Research Institute, Vancouver, BC, Canada; 20Stanford University Medical Center, Stanford, CA, USA; 21Toronto Liver Centre, Toronto, ON, Canada; 22Southern California Research Center, Coronado, CA, USA; 23Asian Pacific Liver Center, Los Angeles, CA, USA; 24Institute of Liver Studies, King's College Hospital, London, UK; 25Department of Medicine and State Key Laboratory of Liver Research, Queen Mary Hospital, The University of Hong Kong, Hong Kong
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