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Decreased Myelin Content and Cognitive Performance in Adults with Perinatal HIV
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CROI 2022 Feb 11-16
Motor dysfunction is a complex interaction of brain injury location, developmental plastic adaptation, and multiple physical factors over time such as weakness, dexterity, tone, musculoskeletal issues, and factors inherent to the individual child.
Motor Impairment is a major cause of physical disability and includes muscle weakness and fatigue, impaired sensation and poor balance, and muscle contracture and spasticity - all of which need to work if we are to undertake the usual range of daily activities.
https://www.neura.edu.au/research-centre/motor-impairment/
https://motorimpairment.neura.edu.au/
Pathological changes of certain areas of the brain are the main causes of most motor disorders.[4] Causes of motor disorders by genetic mutation usually affect the cerebrum.[5] The way humans move requires many parts of the brain to work together to perform a complex process. The brain must send signals to the muscles instructing them to perform a certain action. There are constant signals being sent to and from the brain and the muscles that regulate the details of the movement such as speed and direction, so when a certain part of the brain malfunctions, the signals can be incorrect or uncontrollable causing involuntary or uncontrollable actions or movements.[4]
https://en.wikipedia.org/wiki/Motor_disorder
Motor impairment
Motor impairment is the partial or total loss of function of a body part, usually a limb or limbs. This may result in muscle weakness, poor stamina, lack of muscle control, or total paralysis. Motor impairment is often evident in neurological conditions such a cerebral palsy, Parkinson’s disease, stroke and multiple sclerosis.
Neural interfaces have been explored to restore functionality for severely motor-impaired individuals. Implanted devices in the area of the brain’s motor cortex sense brain states, and the interpreted signals are transmitted to a computer. With training, users develop some command over objects in the environment, which could be applied to such basic efforts as communicating or moving a motorized wheelchair.
https://www.neuromodulation.com/motor-impairment
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