Weight Gain: Does what Goes Up Come Down ? Themed Discussion
CROI 2023 Feb 20-23
• switch to TAF/FTC/DTG to TDF/3TC/DTG, weight decrease
• switch to DTG/3tc, favorable metabolic profile
• reversibility of weight gan if switched off TSF and/or INSTI
• switching off nevirapine vs EFV to DTG does not result in weight gain
• metabolic changes after switch to LA CAB/RPV from Biktarvy