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People living with HIV at substantially higher risk of depression and suicide, especially in first 2 years after diagnosis….reported yesterday at 33rd ECCMID in Denmark
  conference abstract, press release:
Overall, PLWH had double the risk of depression and treatment with ECT compared to controls, 1.5 times greater risk of antidepressant use, and 3.5 times increased risk for suicide (see table 1 and figure 1 in notes to editors). The risks were much higher in the 2 years after diagnosis.
People living with HIV at substantially higher risk of depression and suicide, especially in first 2 years after diagnosis - (04/18/23)


Rates and risk factors for suicidal ideation, suicide attempts and suicide deaths in persons with HIV: a systematic review and meta-analysis - (04/18/23)
About 40 million people of the global population are currently living with HIV/AIDS.3 32 The era of HAART treatment has brought significant improvements in patient longevity and quality of life; however, PLWHA experience a heavy burden of psychosocial conditions that are frequently undiagnosed and untreated. In our study, the pooled incidence of suicide completion among PLWHA globally was 10.2 per 1000 (95%CI: 4.5 to 23.1), translating to a 100-fold greater suicide completion rate compared with the global population rate of 0.11/1000.33
The overall pooled incidence of suicide attempts per 1000 population was 20.4 (95%CI: 2.4 to 154.9) (figure 3). The incidence in North America was 50 times as high compared with that in Europe. Likewise, in PLWHA, the lifetime prevalence of suicide attempts was 158.3 per 1000 persons (95%CI: 106.9 to 228.2).
Additionally, the overall pooled prevalence of suicidal ideation in PLWHA was 228.3/1000 (95%CI: 150.8 to 330.1). This is markedly increased compared with the global suicidal ideation rate of 9% in the general population.34


Cecilie V. Vollmond, B.M.Sc., Malte M. Tetens, M.D., Fie W. Paulsen, B.M.Sc., Jan Gerstoft, M.D., D.M.Sc., Gitte Kronborg, M.D., D.M.Sc., Isik S. Johansen, M.D., D.M.Sc., Carsten S. Larsen, M.D., D.M.Sc., Lothar Wiese., M.D., Ph.D., Michael Dalager-Pedersen, M.D., Ph.D., Steffen Leth M.D., Ph.D., Preben B. Mortensen, M.D., D.M.Sc., Anne-Mette Lebech, M.D., D.M.Sc., Niels Obel, M.D., D.M.Sc., Lars H. Omland, M.D., D.M.Sc.


Aim: To analyze the risk of depression among PWH compared with the background population in Denmark and the impact of family related factors.





This work was supported by Gilead 2022 (Nordic Fellowship [unrestricted research grant to A.M.L.]). The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

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