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New antiretrovirals and HIV treatment strategies - Plenary
Long-acting technologies: A game changer?
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IAS 2023 july 24
( C. CORTES )
NOT TRUE the study reported in JAMA 6 years less life expectancy if started ART with 500 or more CD4 !
"From 2011 to 2016, overall life expectancy at 21 years of age for individuals with HIV infection who initiated ART at a CD4 cell count of 500/μL or greater was 57.4 years (95% CI, 55.7-59.1 years) and for uninfected adults was 64.2 years (95% CI, 64.0-64.4 years), corresponding to a difference of 6.8 years (95% CI, 5.0-8.5 years) (Table 3)."
"Even among individuals with HIV infection who initiated ART at CD4 cell counts of 500/μL or greater, a 7-year difference persisted.
Furthermore, the difference in comorbidity-free life expectancy did not improve over time, and age-related comorbidities occurred 16 years earlier among individuals with HIV infection than among HIV-uninfected individuals (2014-2016). ” Collins & Armstrong Commentary
JAMA Pdf attached
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