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In the era of effective antiviral therapy, cured hepatitis C remains a main cause of HCC
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EASL 2024 June 5-8 Milan, Italy
Elena Vargas-Accarino1, Monica Higuera1, Maria Buti1 2 3 4, Beatriz Minguez1 2 3 4
1Liver Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain, 2Department of Medicine, Campus de la UAB, Universitat Autňnoma de Barcelona (UAB), Barcelona, Spain, 3Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain, 4Liver Unit, Hospital Universitario Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain
In conclusion, alcohol-related liver disease & hepatitis C were the main causes of HCC in our center in recent years, in the era of total accessibility to DAA, the development of HCC in HCV-related liver disease patients remains a significant concern, especially in those with advanced fibrosis & cirrhosis, MASLD-related HCC, although growing globally, was not relevant in our data, accounting for only 13% of our patients. further studies will be necessary to establish MASLD's influence in the shared risk factors, promoting the progression to an inflammatory state, and triggering carcinogenesis.
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